One third of the patients that suffer from pharmacoresistant focal epilepsy are potential candidates for therapeutic surgery. The goal of epilepsy surgery is to remove, disconnect or inactivate the epileptogenic cortex to obtain seizure freedom. A correct presurgical identification of the epileptogenic zone (EZ) has an impact on postsurgical outcome. In 20–50% of the patients candidate to surgery, invasive recordings by intracerebral stereo-electroencephalographic (SEEG) electrodes is necessary to identify the boundaries of the EZ. This Epilepsiechirurgie und SEEG Group founded to research, develop and apply a new technological approaches to facilitate this process. A full spectrum of the available technics (Video-EEG, MRI, PET, SPECT, SEEG) are used to identify biomarkers for the epileptogenic network during presurgical evaluation and SEEG implantation planning. The main focus of the group is developing a computational tools for SEEG analisys, seizure detection and surgery planning. This require a strong multidisciplinary expertise and collaborations. We are open to motivated persons to join us in this adventure.


Elpho-EEG™ is a computer software compiled in Labview to analyze the frequency content of intracranial EEG signals in more than 200 simultaneously recorded channels. Elpho-EEG™ was developed by Vadym Gnatkovsky in collaboration with the Unit of Epileptology and Experimental Neurophysiology of the Fondazione IRCSS Istituto Neurologico Carlo Besta and Claudio Munari Epilepsy Surgery Center at the Niguarda Hospital (Milano, Italy). The software has been successfully used in last years to support EEG signal analysis in studies published in peer-reviewed Journals and presented at neuroscience and epilepsy International meetings.
More information can be here.


AIM:  Gnatkovsky Lab aims to advance the understanding (interpretation), application (implantation schemes), and standardization of SEEG (stimulation, data analysis) and enhance diagnostic accuracy, therapeutic efficacy, and overall patient outcomes in the Bonn Epilepsy surgery program

State of the art Protocols: Implement best practice protocols for the acquisition, interpretation, and reporting of SEEG data, supporting electrode placement, recording parameters, and post-processing techniques

Clinical Case Reviews: Facilitate regular case review sessions to discuss challenging clinical cases utilizing SEEG, encouraging cross-disciplinary discussions involving neurologists, neurosurgeons, and other relevant specialists

Training & Education: Develop training programs for clinicians/researchers interested in SEEG, provide educational resources, workshops, and mentorship opportunities to enhance expertise in SEEG methodology

Technology Integration: Explore and evaluate emerging technologies for SEEG, including advancements in electrode design, imaging modalities, and signal processing, and foster collaborations with industry partners to promote the development of innovative SEEG analysis tools

Collaborative Research Projects: Initiate and support collaborative research projects in epilepsy and neurophysiology; encourage cross-institutional collaborations


… your comments are very welcome!

Hallo World!

This is the first post of the New Year 2024! (actually first post in this blog ) I wish you all the best in the New Year, and all your dreams comes true! Hope to see you around.. Happy New Year!